{"id":1877,"date":"2016-10-21T12:49:47","date_gmt":"2016-10-21T10:49:47","guid":{"rendered":"http:\/\/k1nytt.w.uib.no\/?p=1877"},"modified":"2016-10-21T12:49:47","modified_gmt":"2016-10-21T10:49:47","slug":"ukens-publikasjon-uke-42","status":"publish","type":"post","link":"https:\/\/k1nytt.w.uib.no\/en\/2016\/10\/21\/ukens-publikasjon-uke-42\/","title":{"rendered":"Ukens publikasjon, uke 42"},"content":{"rendered":"

English below<\/span>
\nDenne ukens publikasjon er fra seksjon for psykiatri, der Professor Ole Bernt Fasmer er seksjonsleder. <\/strong>PhD-kandidat og psykiater Tone Elise Gj\u00f8tterud Henriksen er f\u00f8rsteforfatter p\u00e5 artikkelen som seksjonen ville presentere: \u00abBlue-Blocking Glasses as Additive Treatment for Mania: a Randomized Placebo-controlled Trial\u00bb https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27226262<\/u><\/a><\/strong><\/p>\n

Bakgrunnen for studien var sv\u00e6rt lovende rapporter om rask bedring av mani ved bruk av m\u00f8rkt rom i 14 timer i d\u00f8gnet, og oppdagelsen av en bl\u00e5lysf\u00f8lsom reseptor i \u00f8yet som registrerer lys for regulering av d\u00f8gnrytme og v\u00e5kenhet. Blokkering av bl\u00e5tt lys skaper et virtuelt m\u00f8rke i hjernen.<\/p>\n

Behandlingseffekten av 14 timer i d\u00f8gnet med bl\u00e5blokkerende oransje briller ved mani i tillegg til ordin\u00e6r medikamentell behandling ble unders\u00f8kt, sammenliknet med klare placebo-briller. Resultatet viste en rask reduksjon av maniske symptomer i gruppen som fikk oransje briller, med signifikant forskjell mellom gruppene etter bare tre dagers behandling. Resultatene fra studien, som ble publisert i niv\u00e5 2 tidsskriftet Bipolar Disorders<\/em> (mai 2016) har bidratt til \u00e5 bane veg for utbredelse av denne nye behandlingsformen ved bipolar lidelse.<\/p>\n

\"Uken<\/p>\n

Figure 2.<\/strong>
\na) Young Mania Rating Scale Total Scores for Patients Assigned to Blue-Blocking (BB) Glasses (n=12*) or Clear Glasses (Placebo) (n=11**), Means with 95%CI<\/strong><\/p>\n

The p-values of the linear model analyses of group differences using time\/treatment interaction for all time points compared with the baseline values on top of figure.<\/p>\n

<\/p>\n

This weeks\u2019 publication is from section of psychiatry, led by Professor Ole Bernt Fasmer. PhD candidate and psychiatrist Tone Elise Gj\u00f8tterud Henriksen was the first author of the study: \u00abBlue-Blocking Glasses as Additive Treatment for Mania: a Randomized Placebo-controlled Trial\u00bb https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27226262<\/span><\/u><\/a><\/strong><\/p>\n

The study was motivated by promising results of dark therapy; use of dark room at late evening and night for reducing manic symptoms and stabilizing bipolar mood-swings, and the discovery of a blue light sensitive receptor in the eye that detects light for day signal to the brain.<\/p>\n

This way blue-blocking eyewear creates a virtual darkness state in the brain with regards to circadian (daily) rhythms in the brain and the rest of the body.<\/p>\n

Patients were assigned blue-blocking glasses or placebo (clear glasses) from 6 p.m. to 8 a.m. for seven days, in addition to treatment as usual. The difference in manic symptoms between groups was significant after three days (p=0.042) and continued to increase throughout the intervention (p=0.001 after seven days). The study was published in Bipolar Disorders (May 2016) and has contributed to dissemination of this new treatment option for bipolar mania.<\/p>","protected":false},"excerpt":{"rendered":"

English below Denne ukens publikasjon er fra seksjon for psykiatri, der Professor Ole Bernt Fasmer er seksjonsleder. PhD-kandidat og psykiater Tone Elise Gj\u00f8tterud Henriksen er f\u00f8rsteforfatter p\u00e5 artikkelen som seksjonen ville presentere: \u00abBlue-Blocking Glasses as Additive Treatment for Mania: a…<\/p>\n

Read more →<\/a><\/p>","protected":false},"author":3633,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1219],"tags":[],"class_list":["post-1877","post","type-post","status-publish","format-standard","hentry","category-forskning"],"_links":{"self":[{"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/posts\/1877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/users\/3633"}],"replies":[{"embeddable":true,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/comments?post=1877"}],"version-history":[{"count":7,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/posts\/1877\/revisions"}],"predecessor-version":[{"id":1908,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/posts\/1877\/revisions\/1908"}],"wp:attachment":[{"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/media?parent=1877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/categories?post=1877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/k1nytt.w.uib.no\/en\/wp-json\/wp\/v2\/tags?post=1877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}